VP or SVP of Clinical Development
San Diego, CA
Full Time
ClinGen - ClinOps
Senior Executive
About Radionetics
Radionetics Oncology, Inc. is a clinical stage company focused on the discovery and development of novel radiopharmaceuticals for the treatment of a wide range of oncology indications and is poised to capitalize on the increasing demand for novel radiotherapeutics. Radionetics Oncology is supported by Frazier Life Sciences, 5AM Ventures, DCVC Bio, Crinetics Pharmaceuticals, and GordonMD Global Investments and has entered into a strategic agreement with Eli Lilly. Radionetics is advancing a pipeline of first-in-class small molecule radioligands targeting G protein coupled receptors for the treatment of a broad range of cancers, including breast cancer, lung cancer, and other indications of high unmet need.
Position summary
The VP/ Senior VP of Clinical Development, is a critical leadership role working closely with the CMO on the design, execution, and interpretation of clinical trials for our novel radiopharmaceutical pipeline in oncology. This individual will serve as a medical and scientific lead for assigned programs, providing strategic and operational direction to advance our innovative therapies through first-in-human studies.
The successful candidate will be a board-certified Medical Doctor (MD) with significant experience in oncology drug development, preferably with specific expertise in radioligand therapy (RLT) or nuclear medicine. The exact title (Medical Director, VP, SVP) will be determined based on the candidate's experience, scope of responsibility, and proven track record.
Essential job functions and duties
I. Clinical Strategy & Execution (Primary Focus)
Radionetics has a competitive total compensation package that includes bonus opportunity; equity; medical, dental, vision, life, short-term, and long-term disability insurance; 401(k) retirement plan with employer match; 4 weeks of paid time off (PTO) annually; and generous paid holidays.
Pay Range
The pay range for this position is $315,000 to $415,000 and dependent on the level of position hired. Radionetics evaluates a variety of factors in determining individual pay decisions, which may include relevant education, experience, and skills; internal equity; complexity and responsibility of the role; and market demand relative to the position. Geographic location may also be a consideration in evaluating salary when candidates work in states outside of California.
Important notices
Radionetics Oncology, Inc. is committed to a policy of equal opportunity in which all qualified applicants receive equal consideration for employment without regard to race, color, national origin, ancestry, religion, sex, pregnancy, marital status, sexual orientation, gender, gender identity and expression, age, physical and medical disability, medical condition, genetic information, military or veteran status, or any other federal, state or local protected class.
The job description specifics provided above are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities and requirements. Radionetics retains the right to add or change duties, education, experience, skills or any other requirements of the position at any time.
Radionetics does not accept unsolicited referrals from employment agencies for position vacancies unless written authorization is provided from the Human Resources department before any candidates are referred for specific identified positions. In the absence of such written authorization, any actions taken by the employment business/agency shall be deemed to have been performed without consent or contractual agreement, and Radionetics shall not be liable for any fees arising from such actions or referrals for position vacancies at Radionetics.
Radionetics Oncology, Inc. is a clinical stage company focused on the discovery and development of novel radiopharmaceuticals for the treatment of a wide range of oncology indications and is poised to capitalize on the increasing demand for novel radiotherapeutics. Radionetics Oncology is supported by Frazier Life Sciences, 5AM Ventures, DCVC Bio, Crinetics Pharmaceuticals, and GordonMD Global Investments and has entered into a strategic agreement with Eli Lilly. Radionetics is advancing a pipeline of first-in-class small molecule radioligands targeting G protein coupled receptors for the treatment of a broad range of cancers, including breast cancer, lung cancer, and other indications of high unmet need.
Position summary
The VP/ Senior VP of Clinical Development, is a critical leadership role working closely with the CMO on the design, execution, and interpretation of clinical trials for our novel radiopharmaceutical pipeline in oncology. This individual will serve as a medical and scientific lead for assigned programs, providing strategic and operational direction to advance our innovative therapies through first-in-human studies.
The successful candidate will be a board-certified Medical Doctor (MD) with significant experience in oncology drug development, preferably with specific expertise in radioligand therapy (RLT) or nuclear medicine. The exact title (Medical Director, VP, SVP) will be determined based on the candidate's experience, scope of responsibility, and proven track record.
Essential job functions and duties
I. Clinical Strategy & Execution (Primary Focus)
- Clinical Program Leadership: Serve as a medical lead for one or more radioligand therapy programs. Develop and drive the clinical development plan, ensuring alignment with regulatory requirements and the company’s strategic goals.
- Trial Design: Work closely with the CMO on the design and preparation of clinical trial protocols (first-in-human), statistical analysis plans, and clinical study reports. This includes defining patient populations, endpoints, and appropriate dose escalation strategies.
- Study Oversight: Provide ongoing medical monitoring and real-time support for clinical trials, including reviewing and interpreting clinical data, assessing safety signals, and determining the medical eligibility of subjects.
- Data Interpretation: Perform clinical data review and interpretation, including the preparation of top-line results, integrated summaries of safety and efficacy, and final reports.
- Regulatory Interaction: Serve as a medical expert in interactions with regulatory authorities globally. Prepare and present clinical data during meetings to support regulatory filings and development.
- Collaborative Leadership: Work closely with cross-functional teams, including Research & Discovery, Translational Medicine, Biostatistics, Clinical Operations, Regulatory Affairs, and CMC to ensure seamless program execution, recognizing the unique supply chain and manufacturing needs of RLTs.
- External Expertise and Communication: Establish and maintain relationships with key opinion leaders (KOLs), investigators and clinical site staff to garner clinical insights. Travel to sites to enhance engagement and drive clinical trial enrollment.
- Publications & Presentations: Lead the preparation of clinical trial results for publication in peer-reviewed journals and presentation at major scientific congresses (e.g., ASCO, ESMO, SNMMI).
- Internal Communication: Provide internal medical and scientific training to internal teams (e.g., business development, commercial, medical affairs) as needed.
- Education: M.D. required. Board Certification/Eligibility in Oncology, Hematology/Oncology, or Nuclear Medicine is highly preferred.
- Experience: Minimum 6-12+ years of industry clinical development experience, with a focus on oncology. Progressive leadership experience in clinical development, with demonstrated ability to define and execute global clinical strategies for complex therapeutics.
- Oncology Expertise: Deep knowledge of the oncology landscape, including standard of care, translational research, and emerging therapeutic modalities.
- Clinical Trial Expertise: Proven experience designing, implementing, and medically overseeing first-in-human/ Phase 1 clinical trials.
- Direct experience with the development, clinical application, or regulatory aspects of radiopharmaceuticals, targeted radionuclide therapy, or nuclear medicine.
- Understanding of the unique safety, handling, and logistics challenges associated with radioligand therapies.
- The position is based in San Diego, CA; a portion of the job duties may be performed remotely.
- Domestic and international travel may be required up to 30%.
Radionetics has a competitive total compensation package that includes bonus opportunity; equity; medical, dental, vision, life, short-term, and long-term disability insurance; 401(k) retirement plan with employer match; 4 weeks of paid time off (PTO) annually; and generous paid holidays.
Pay Range
The pay range for this position is $315,000 to $415,000 and dependent on the level of position hired. Radionetics evaluates a variety of factors in determining individual pay decisions, which may include relevant education, experience, and skills; internal equity; complexity and responsibility of the role; and market demand relative to the position. Geographic location may also be a consideration in evaluating salary when candidates work in states outside of California.
Important notices
Radionetics Oncology, Inc. is committed to a policy of equal opportunity in which all qualified applicants receive equal consideration for employment without regard to race, color, national origin, ancestry, religion, sex, pregnancy, marital status, sexual orientation, gender, gender identity and expression, age, physical and medical disability, medical condition, genetic information, military or veteran status, or any other federal, state or local protected class.
The job description specifics provided above are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities and requirements. Radionetics retains the right to add or change duties, education, experience, skills or any other requirements of the position at any time.
Radionetics does not accept unsolicited referrals from employment agencies for position vacancies unless written authorization is provided from the Human Resources department before any candidates are referred for specific identified positions. In the absence of such written authorization, any actions taken by the employment business/agency shall be deemed to have been performed without consent or contractual agreement, and Radionetics shall not be liable for any fees arising from such actions or referrals for position vacancies at Radionetics.
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